Acne

Where can I buy Accutane (Isotretinoin) Online

Annoying pimples appear at the most inopportune moments in life. Acne on the face brings significant discomfort. Although acne is not accompanied by severe pain, it is a cosmetic defect that reduces self-esteem and self-confidence.

There are many reasons for the occurrence of skin disease, from hormonal imbalance to improper cosmetic care. For severe rashes, medications come to the rescue.

Accutane is a drug containing isotretinoin as an active ingredient. This compound is similar in structure to tretinoin or the acid form of vitamin A, a recognized assistant in the fight against acne.

Accutane: what is it for?

An important question to ask before using Accutane is what the medication does. So, the capsules suppress the activity of the sebaceous glands and reduce their size, which improves the clinical picture of severe forms of acne.

Indications for Accutane include various types of acne, including nodular cystic acne, acne with an increased risk of scarring, and acne that does not respond to other types of treatment.

Pharmacologic effect

The active component of the drug is isotretinoin. It has anti-inflammatory and antimicrobial effects. The substance is capable of normalizing the functioning of regeneration, reduction, and oxidation processes.

The component destroys the expression of genes responsible for protein production, has a positive effect on microflora, and prevents infectious diseases.

The action of the drug stops the production of sebum so that the skin remains clean for a long period of time and the pores are not contaminated. Isotretinoin is successfully used both in dermatology and cosmetology.

The drug is a systemic retinoid. This group of medications restores skin regeneration and inhibits excess sebum in the skin. The drug affects the genitourinary, nervous, musculoskeletal systems, as well as the stomach and intestines.

Accutane: dosage

The drug is available in two dosages: 10 mg and 20 mg. Therapy should be prescribed and adjusted by a physician who has experience in the use of such drugs and a full understanding of the risks. The dosage of the drug is selected individually and, as a rule, starts with 0.5 mg per kilogram of body weight per day.

The cumulative dose of Accutane, or in other words, the concentration of the drug that provides a lasting therapeutic effect, is 120-150 mg/kg. This dosage is necessary for severe and moderate acne.

Accutane: contraindications

It is not advisable to take Accutane together with certain medications. For example, Accutane is contraindicated when taking tetracycline antibiotics.

Other contraindications:

• Hypersensitivity to the components of the drug
• Liver dysfunction
• Increased concentration of vitamin A in the body
• Excessive fat content in the body
• Children under 12 years of age

It is not advisable to take Accutane together with certain medications. For example, Accutane is contraindicated when taking tetracycline antibiotics.

Accutane side effects

Side effects of Accutane are reversible and disappear after dose adjustment or discontinuation of the drug, but some remain even after discontinuation of therapy.

The full list can be found in the instructions, but the most common adverse reactions include:

• Thrombocytopenia – decreased number of platelets in the blood
• Increased erythrocyte sedimentation rate
• Headache
• Dry and irritated eyes
• Hearing impairment
• Nose bleed
• Increased activity of liver enzymes
• Dermatitis and skin fragility
• Pain in muscles, joints, and back
• Increased cholesterol

Accutane prescription during pregnancy and lactation

Pregnancy poses a significant risk for individuals undergoing Accutane therapy due to its potent teratogenic effects. Despite warnings, if pregnancy occurs during treatment or within a month after therapy cessation, there is a high likelihood of severe birth defects in the child.

Accutane, also known as isotretinoin, carries a strong teratogenic potential. Any instance of pregnancy while a woman is taking isotretinoin orally, regardless of dosage or duration, significantly increases the chances of the child being born with developmental abnormalities.

Given these risks, Accutane is contraindicated for women capable of bearing children. Their healthcare provider should thoroughly discuss the potential for pregnancy during Accutane treatment. Effective contraception must be consistently used for one month before starting Accutane, throughout the treatment period, and for one month post-treatment.

It's crucial to emphasize the necessity of contraception, as described above, even for women who typically do not use it due to reasons such as infertility (excluding those who have undergone a hysterectomy), amenorrhea, or reported sexual inactivity.

Accutane and alcohol

The compatibility of Accutane and alcohol is another serious issue. The instructions for the drug say that high-risk patients, including patients with a history of alcoholism, require frequent monitoring of blood glucose and lipid levels. However, you should not drink alcohol during therapy.

The drug already has an impressive list of adverse reactions, and additional ethanol will intensify them many times over.